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Parkinson’s disease is a nervous system disorder that affects movement, causing slowness, stiffness, walking and balance problems, and in later stages, tremors. Over time, patients diagnosed with PD experience a worsening of symptoms.

In the early stages of Parkinson’s, symptoms may be mild and can be easy to miss. These symptoms include:

  • Slowed movement, also known as bradykinesia (steps are shorter when you walk, difficulties getting out of a chair, feet drag while walking, etc.)
  • Rigid facial expressions
  • Muscle stiffness that can be painful and limit your range of motion
  • Changes in speech (becomes soft and slurred)
  • Changes in writing (hard to write, writing becomes smaller)
  • Losing your sense of smell
  • Depression and emotional changes (fear, anxiety, loss of motivation)


image of an older man rubbing his hand

Lack of Treatment Options

There are no current treatments that reverse, stop, or slow down the progressive loss of neuron function in patients with Parkinson’s disease. The treatments that do exist treat only the symptoms associated with PD and provide only temporary improvement. These options often become less effective over time.

As a patient diagnosed with early-stage Parkinson’s disease who has not yet received treatment for PD, your participation in clinical trials could help advance the development of treatment options for this disease. You can make a difference by filling a critical need for study volunteers in these trials.

PRISM Parkinson’s Research Study Enrolling Now

Complete the online eligibility questionnaire to see if you pre-qualify:

Refer a Friend

Do you know someone (ages 30 to 80) diagnosed with early-stage Parkinson’s disease (PD) who has not yet received medication for PD? They may be eligible to participate in this research study.